Atopic dermatitis. Atopic dermatitis
Conditions
Interventions
Intervention 1: Patients in intervention group should use the azathioprine-betamethasone emolient cream twice daily for 8 weeks on cutaneous lesions of the whole body except for face. Intervention 2:
Treatment - Drugs
Patients in intervention group should use the azathioprine-betamethasone emolient cream twice daily for 8 weeks on cutaneous lesions of the whole body except for face.
Patients in control group should use betamethasone emolient cream twice daily for 8 weeks on all cutaneous lesions of the body except for face.
Sponsors
Vice Chancellor for research of Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: children older than 2 years; patients with no enough response to conventional topical therapies in recent past 6 months; patients who do not receive any systemic drug which interacts with azathioprine in recent past 1 month; patients whose lesions are not limited to the face; patients with out any liver and bone marrow dysfunction. Exclusion criteria: any labratory abnormality; patients who do not desired to stay in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical severity of cutaneous lesions. Timepoint: At baseline, at the end of the treatment course(8th week), one month after the cessation of the treatment. Method of measurement: SCORAD index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence of cutaneous lesions. Timepoint: 1 month after the cessation of the treatment. Method of measurement: Physical exam and history taking. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Sadaf Farhadi
Skin disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences
Outcome results
None listed