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Single dose versus triple dose of antibiotic in prophylaxis of wound infection in acute appendicitis: prospective randomized study

Single dose versus triple dose of antibiotic in prophylaxis of wound infection in acute appendicitis: prospective randomized study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014092219255N1
Enrollment
150
Registered
2014-10-02
Start date
2013-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

surgical infection. Other complications of obstetric surgery and procedures

Interventions

Intervention 1: The intervention group received diet antibiotic metronidazole 500 mg single dose and one gram of ceftriaxone intravenously before surgery. Intervention 2: Under the control of antibiot
Treatment - Drugs
The intervention group received diet antibiotic metronidazole 500 mg single dose and one gram of ceftriaxone intravenously before surgery
Under the control of antibiotic metronidazole 500 mg single dose or two doses of one gram of ceftriaxone intravenously before surgery and after surgery (continuing until 24 hours after surgery) as wel

Sponsors

Vice Chancellor for Research and Technology, Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with acute suppurative appendicitis are pleased to participate in the study Exclusion criteria: Patients with a normal appendix; gangrenous; perforated; a patient endocarditis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Infection. Timepoint: One month. Method of measurement: Clinical.

Secondary

MeasureTime frame
Fever and chills. Timepoint: 24 hours after surgery. Method of measurement: Clinical.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026