migraine headache. Migraine, unspecified
Conditions
Interventions
Intervention 1: in cases each green capsule contains350±5miligeram extract of licorice ,it is equal with 1400±20miligeram of powder of root of licorice, that will be taken 2capsule 3times a day(at
Treatment - Drugs
Placebo
in cases each green capsule contains350±5miligeram extract of licorice ,it is equal with 1400±20miligeram of powder of root of licorice, that will be taken 2capsule 3times a day(at morning,noon,nig
In controls each green capsule contains 350±5miligeram starch,that will be taken 2capsules of starch 3times a day(at morning,noon,night) with a glass of water .as totally daily dosage will be 2
Sponsors
Shiraz University of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:40 patients with migraine (age18to80y/o)with systolic blood pressure lower than 120mmhg,for prophylactic management of migraine with propranolol are enrolled. Exclusion criteria: patients with hypertension or related remedies, liver, renal, adrenal,diabetic diseases, as well as pregnant participants and those sensitive to licorice are excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of headache. Timepoint: before and 3months after intervention. Method of measurement: counting.;Frequency of dizziness. Timepoint: before and 3months after intervention. Method of measurement: counting.;Prevalence of dizziness. Timepoint: before and 3months after intervention. Method of measurement: report of patient.;Severity of dizziness. Timepoint: before and 3months after intervention. Method of measurement: numeric scale in 5level.;Systolic blood pressure. Timepoint: before and 3months after intervention. Method of measurement: mmhg with mercurial manometer.;Diastolic blood pressure. Timepoint: before and 3months after intervention. Method of measurement: mmhg with mercurial manometer.;Orthostatic hypotension. Timepoint: before and 3months after intervention. Method of measurement: with mercurial manometer in sleeping ans standing up position after 2minutes.;Severity of headache. Timepoint: before and 3months after intervention. Method of measurement: pain scale0-10.;Severity of headache. Timepoint: before and 3months after intervention. Method of measurement: migraine disability assesment score test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum potassium. Timepoint: 6weaks after intervension. Method of measurement: sampling from patients serum,meq per liter.;Weight. Timepoint: before and3months after intervension. Method of measurement: Kg with Digital weighing- machine. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Bahrami
Shiraz University of Medical Science
Outcome results
None listed