Effect of Ondansetron and Granisetron For The Prevention Of Pruritus In Patients Undergoing Cesarean Section

Comparing the Prophylactic Effect of Intravenous Ondansetron And Granisetron On Pruritus after Intrathecal Morphine in Elective Cesarean Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014092219252N1

Enrollment

Registered

2014-10-05

Start date

2014-03-12

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pruritus. Pruritus, unspecified

Interventions

Intervention 1: Group1: injection 8 mg ondansetron before intrathecal morphine. Intervention 2: Group2: injection 3mg granisetron before intrathecal morphine. Intervention 3: Group3: injection 4mg nor

Prevention

Placebo

Group1: injection 8 mg ondansetron before intrathecal morphine

Group2: injection 3mg granisetron before intrathecal morphine

Group3: injection 4mg normal salin before intrathecal morphine

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Women undergoing elective cesarean section with spinal anesthesia. Exclusion criteria: Drug addiction; history of allergy to ondansetron, granisetron and morphine; electrolyte abnormalities; history of pruritic skin diseases and other systemic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pruritus. Timepoint: 3, 6 and 18 hour after intrathecal morphine. Method of measurement: visual analog scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Kohani

Ahwaz Jondishapour University of Medical Sciences

Kohani.sarah@gmail.com+98 61 1221 6504

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026