The effect of continuous heparin infusion on the duration of central venous catheter patency in preterm infants

The effect of continuous heparin infusion on the duration of open peripheral central venous catheter (PICC) patency in preterm neonates

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140921019250N2

Enrollment

126

Registered

2020-02-20

Start date

2018-03-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature babies. Preterm [premature] newborn [other]

Interventions

Intervention 1: Intervention group: The study group (administration of intravenous fluids containing 0.5 U / ml / hr) will receive two dextrose-based injections containing amino acid and lipid. Unbrok

Eligibility

Sex/Gender

All

Age

No minimum to 9 Months

Inclusion criteria

Inclusion criteria: All premature infants (gestational age less than 34 weeks) admitted to NICU ward of Alzahra hospital in Tabriz who require PICC catheter insertion

Exclusion criteria

Exclusion criteria: Infants with a bleeding tendency Grade 3 and 4 intravascular hemorrhage Newly diagnosed sepsis Thrombocytopenia DIC arrhythmia Congenital malformations Increased PTT (more than 71 seconds) Babies in need of heparin Babies in need of heparin

Design outcomes

Primary

Measure	Time frame
Duration of catheter use is the time between insertion and exit of the catheter due to obstruction. Timepoint: On the first and seventh day, and immediately after the catheter was removed. Method of measurement: Sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Majid Mahallei

Tabriz University of Medical Sciences

medicalresearchtbz@gmail.com+98 41 3385 1949

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026