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Evaluation the prescription effect of Novafen versus combination of Acetaminophen codeine and Ibuprofen on pain

Evaluation the effect of Novafen prescription versus combination of Acetaminophen codeine and Ibuprofen on pain after surgical extraction of wisdom teeth

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014091919228N1
Enrollment
80
Registered
2014-12-19
Start date
2014-12-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impacted teeth. An impacted tooth is a tooth that has failed to erupt because of obstruction by another tooth.

Interventions

Intervention 1: tablet Novafen 400 mg ,each 8 hours after surgery,for 1 week (20 numbers). Intervention 2: tab acetaminophen codein 320 mg and ibubrofen 200 mg each 8 hours after surgery,for one week.
Treatment - Drugs
tablet Novafen 400 mg ,each 8 hours after surgery,for 1 week (20 numbers)
tab acetaminophen codein 320 mg and ibubrofen 200 mg each 8 hours after surgery,for one week

Sponsors

Research center,kerman university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:1. age between 18-30 2.physical status ASA 1,2 3.without analgesic use history 4.without oral and maxillofacial surgery history 5.without oral and maxillofacial trauma history 6.having one mesioangular lower third molar with pell & gregory class I ,A 7.without previous wisdom teeth surgery 8.without using alcohol and narcotics 9.without asthma history 10.without gastic ulcer and GI bleeding Exclusion criteria: 1.oral and maxillofacial surgery and admission history 2.having any chronic systemic or psychosomatic disease 3.having history or risk of infective endocardititis 4.having bleeding disease or using anticoagulant drugs like asorin 5.using alcohol and narcotics 6.acute local infection 7.allergy to codein or cafeine 8.pregnancy or lactating period

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Analgesic type. Timepoint: each 8 hours after surgery. Method of measurement: mg dose.

Secondary

MeasureTime frame
Pain. Timepoint: 3,6,12,24,48 hours after surgery. Method of measurement: VAS scal.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahand Samieirad

kerman dental school,oral and maxillofacial surgery department

sahand@kmu.ac.ir+98 34 3247 7713

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026