Gastric PH. Other specified diseases of stomach and duodenum
Conditions
Interventions
Intervention 1: Intervention group 1: Ranitidine 50 mg IV bolus injections at the first time and then three bolus doses were administered 50 mg every 8 hours. Intervention 2: The second Intervention g
Treatment - Drugs
Intervention group 1: Ranitidine 50 mg IV bolus injections at the first time and then three bolus doses were administered 50 mg every 8 hours.
The second Intervention group received the ampoule for intravenous ranitidine 6/25 mg in the hours after the bolus injection 50 mg (at the time) used.
Sponsors
Vice Chancellor for Research, Mashhad University of Medical sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: All patients aged over 18 years admitted to the ICU after surgery. Exclusion criteria: Pregnancy; H 2-blocker therapy for 8 hours before starting the study; treatment with antacids before starting the study; renal disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric PH. Timepoint: Before treatment and then every 2 hours for 24 hours. Method of measurement: PH measurements.;Administration of ranitidine in intermittent bolus. Timepoint: In the first, then every 8 hours for 24 hours. Method of measurement: Intermittent bolus.;Administration of ranitidine as a continuous infusion. Timepoint: In the first then each hour. Method of measurement: Continuous infusion.;When the PH is upper than 4. Timepoint: Every 2 hours. Method of measurement: PH measurements. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Arash Peivandi Yazdi
Mashhad University of Medical Sciences
Outcome results
None listed