Compare the treatment of constipation in children with paraffin and polyethylene glycol

Comparison Oral paraffin and Polyethylene Glycol (PEG) in treatment of children with chronic functional constipation.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014091618971N2

Enrollment

160

Registered

2014-10-01

Start date

2014-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Constipation. Functional intestinal disorder, unspecified

Interventions

Intervention 1: The first group was given PEG solution with dose 1 cc/kg/day (equivalent 0.8 gr/kg/day of powdered PEG) orally in two divided doses for 6 months. Intervention 2: The second group was g

Treatment - Drugs

The first group was given PEG solution with dose 1 cc/kg/day (equivalent 0.8 gr/kg/day of powdered PEG) orally in two divided doses for 6 months.

The second group was given Paraffin solution with dose 1 cc/kg/day orally in two divided doses for 6 months.

Eligibility

Sex/Gender

All

Age

2 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria include: all children aged 2 to 12 years with chronic functional constipation according to Rome III diagnostic criteria. Exclusion criteria include: have an organic constipation such as Hirschsprung's disease; hyporthyroidism; cardiac; renal and neurologic disorders; history of gastrointestinal surgery and drug use especially anticonvulsants; sedatives and antidepressants.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The number of bowel movements per week. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Stool consistency. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Painful defecation. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.	—

Measure

Time frame

The number of bowel movements per week. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Stool consistency. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Painful defecation. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.

—

Secondary

Measure	Time frame
Rectal bleeding. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Fecal incontinence. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Abdominal pain. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;The side effects of treatment. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.	—

Measure

Time frame

Rectal bleeding. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Fecal incontinence. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;Abdominal pain. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.;The side effects of treatment. Timepoint: Once a week during the first month, then every month until 6 months. Method of measurement: History.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKambiz Eftekhari

Zanjan University of Medical Science

dr_k_eftekhary@yahoo.com+98 24 3313 0001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026