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Evaluation of clinical effects of oral tamsulosin in reducing urinary retention after spine surgery

Evaluation of clinical effects of oral tamsulosin in reducing urinary retention after spine surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140915019185N5
Enrollment
80
Registered
2022-02-06
Start date
2020-12-21
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary retention. Bladder-neck obstruction

Interventions

Intervention 1: Tamsulosin capsule 4 mg mg daily dose started 7 days before surgery and will continue from zero to 2 days after surgery. The type of oral capsule will be provided to the patient. Urina

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Male and female Ability to complete the informed consent form to participate in the study Accepting the schedule of participation in the study and the time of surgery and the fact that she must remain in the hospital for at least 1 night after surgery

Exclusion criteria

Exclusion criteria: Sensitivity or contraindication to the use of tamsulosin Severe hypersensitivity to sulfa drugs Use of the current alpha-blocker (alphazosin, doxazosin, prazosin, terazosin, verapamil, tamsulosin) or oral alpha agonists, or the initiation of any of these drugs during the start of the intervention phase of the study, which will cause the patient to drop out. Take warfarin now Use of a Foley catheter, suprapubic catheter or urostomy Dialysis patients or patients with less than 200 cc of urine per day Predicting the patient's inability to use the drug orally after surgery Lack of conscious consent to participate in the study Patients who use a Foley catheter chronically Patients are expected to be transferred to the ICU after surgery. Patients with a history of severe heart failure or major cardiovascular events in the past 6 months Use beta-blockers, acetylcholinesterase inhibitors, or drugs that interfere with tamsulosin and betanacol.

Design outcomes

Primary

MeasureTime frame
Urinary retention rate. Timepoint: 7 days before surgery and 0 to 2 days after surgery. Method of measurement: sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKaveh Haddadi

Mazandaran University of Medical Sciences

k.haddadi@mazums.ac.ir+98 11 3336 1630

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026