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Comparison of oral pantoprazole and famotidine effect on new bone formation in patients with lumbar spine fusion surgery

Comparison of oral pantoprazole and famotidine effect on new bone formation in patients with lumbar spine fusion surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140915019185N4
Enrollment
58
Registered
2020-11-11
Start date
2020-09-22
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spondylosis. ???? ? ???? ??? ???? ??(??????????)

Interventions

Intervention 1: Intervention group 1: Pentoprazole at a dose of 40 mg once daily for 8 weeks orally. Intervention 2: Intervention group 2: Famotidine at a dose of 40 mg once daily for 8 weeks orally.

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients with degenerative disease requiring lumbar fusion surgery for spinal canal stenosis . patients with degenerative disease requiring lumbar fusion surgery for spondylolisthesis. patients with degenerative disease requiring lumbar fusion surgery for deformity. patients with degenerative disease requiring lumbar fusion surgery including discopathies .

Exclusion criteria

Exclusion criteria: Patients with low back injury due to trauma, infection, tumor, and inflammatory diseases, including rheumatoid arthritis Patients with diabetes Patients who smoke heavily A person's BMI is less than 20 or more than 35 Patients who do not have the consent to enter the study Patients with a history of osteoporosis are treated

Design outcomes

Primary

MeasureTime frame
Bone fusion. Timepoint: Before, three and six months after surgery. Method of measurement: Radiology and CT scan.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKaveh Haddadi

Mazandaran University of Medical Sciences

k.haddadi@mazums.ac.ir+98 11 3335 7255

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026