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Impact of mouthwashes on Mucositis

Comparison of effect of topical utilization of Honey and Chamomile for Prevention on Chemotherapy-induced Mucositis in Children with Leukemia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201409133549N7
Enrollment
40
Registered
2014-10-20
Start date
2014-05-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucositis induced by Chemotherapy in children with Leukemia. ????????? ????? ? ????? ???? ?? ??????????

Interventions

Intervention 1: Honey diluted to a concentration of 12/5%, every two hours during waking hours for 14 days. Intervention 2: Chamomile Mouthwash , Baryj Essence, Kerman, Iran, every two hours during wa
Prevention
Honey diluted to a concentration of 12/5%, every two hours during waking hours for 14 days
Chamomile Mouthwash , Baryj Essence, Kerman, Iran, every two hours during waking hours for 14 days
Positive control, Chlorhexidine, ShahrDaruo, Tehran, Iran, every two hours during waking hours for 14 days
Negative control, Normal saline, Samen, Mashhad, Iran, every two hours during waking hours for 14 days

Sponsors

Vice - Chancellery for Research, Zahedan University of Medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children 1 to 14 years old with Leukemia who were admitted for Chemotherapy in the Zahedan Imam Ali Hospital. Exclusion criteria: Children who underwent Radiotherapy and Surgery in addition to Chemotherapy and Children who also have Systemic Leukemia or other Cancers.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Mucositis. Timepoint: On the first day, Seventh and fourteenth day after starting Chemotherapy. Method of measurement: Based on observation by probe and mirror under headlight.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdieh Hajmohammadi

Dental College of Zahedan University of Medical Sciences

Mahdie.Hajmohammadi@Gmail.Com M_H.Mohammadi@Yahoo.Com+98 54 3342 9482

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026