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comparison of the effect of probiotic yogurt and gums containing xylitol on salivary mutans streptococcus reduction

comparison of the effect of probiotic yogurt and gums containing xylitol on salivary mutans streptococcus reduction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014091319131N1
Enrollment
50
Registered
2015-04-28
Start date
2014-04-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amount of salivary streptococous mutans. Other streptococcal sepsis

Interventions

Intervention 1: Group 1: 200 cc probiotic yoghurt (Kaleh) daily,for 3 weeks, 10 min after dinner. Intervention 2: Group 2: 3 times a day (after 3 meals) 2 pieces (1.86 gr Xylitol) at least for 5 min i
Prevention
Group 1: 200 cc probiotic yoghurt (Kaleh) daily,for 3 weeks, 10 min after dinner.
Group 2: 3 times a day (after 3 meals) 2 pieces (1.86 gr Xylitol) at least for 5 min in a 3-week period Xylitol-containing chewing gum (ORION DR. XYLITOL)

Sponsors

Dental School,Islamic Azad University of Isfahan(Khorasgan)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
73 Years to 58 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:absence of any systemic disease ;having 105= CFU/ml saliva levels of MS Exclusion criteria: had not used antibiotics,cortons,antibacterial mouthwashes;topical fluride(except for fluoride toothpaste),within the 4-week prior to beginningof the study;used daily probiotics and xylitol-containing chewing gums ;person with smoking and used contraceptive drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Salivary mutans sterptococcus reduction. Timepoint: Befor study, immediately one day after complete use of probiotic yoghurt and Xylitol gum (3 weeks) and also 2 & 4 weeks after intervention. Method of measurement: First, saliva samples are cultured on specific medium (Mitis Salivarius Agar) using superficial culture method; eventually, the colonies are visually counted (based on the forming units of colonies in 1ml of saliva (CFU/ml)).

Secondary

MeasureTime frame
Reduction of dental caries. Timepoint: Before study and immediately one day after complete use of probiotic yoghurt and Xylitol gum (3weeks) and also 2 and 4 weeks after intervention. Method of measurement: ????? ????? ??? ???? ??? ???? ??????? Mitis Salivarius Agar ?? ??? ??? ???? ??? ???? ?????? ???? ????? ????? ???? ?? ?? ??? ???? ????? ?? ???(?? ????? ????? ???? ????? ????? ????? ??1 ???? ???????? CFU/ml).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz Ghasemi

Postgraduated Student,Pediatric Dentistery

ghasemi_elnaz_27@yahoo.com El.ghasemi@khuisf.ac.ir+98 31 3535 4053

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026