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Analgesic effect of different doses of granisetron with lidocaine for intravenous regional anesthesia

Analgesic effect of different doses of granisetron with lidocaine for intravenous regional anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014091214056N4
Enrollment
210
Registered
2014-09-23
Start date
2014-05-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regional anesthesia. Local anaesthetics

Interventions

Intervention 1: Intervention group will take 3 mg/kg lidocaine 0.5% with 1 mg granisetron diluted to 40 cc saline 0.9% will infuse over 90 seconds. Intervention 2: Control group will take 3 mg/kg lido
Treatment - Drugs
Intervention group will take 3 mg/kg lidocaine 0.5% with 1 mg granisetron diluted to 40 cc saline 0.9% will infuse over 90 seconds.
Control group will take 3 mg/kg lidocaine 0.5% diluted to 40 cc saline 0.9% will infuse over 90 seconds.

Sponsors

Arak University of Medical Sciences, Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 20 to 50 years old; ASA I or II. Exclusion criteria: history of drug allergy; pregnancy; contraindication of intravenous regional anesthesia like sickle cell anemia; use of opiate and analgesic drugs; use of Apomorphine.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Tourniquet pain. Timepoint: 0, 15, 30 and 45 minute after injection. Method of measurement: VAS.

Secondary

MeasureTime frame
Reduction of pain. Timepoint: Every 30 minutes until 2 hours after removing tourniquet. Method of measurement: VAS.;Vital signs. Timepoint: After removing tourniquet. Method of measurement: Physical examination.;O2 saturation. Timepoint: After removing tourniquet. Method of measurement: Pulse oxymeter.;Need to Fentanyl. Timepoint: 0, 15, 30 and 45 min after injection. Method of measurement: Drug dose that is used.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHesameddin Modir

Vali-e-Asr hospital

he_modir@arakmu.ac.ir+98 86 3223 1104

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026