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The effect of dental pulp mesenchymal stem cells in treatment of corona disease

Study the effect of intravenous injection of dental pulp mesenchymal stem cells in treatment of patients with COVID-19 pneumonia- A Phase 2&3 Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140911019125N8
Enrollment
120
Registered
2020-09-26
Start date
2020-09-10
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corona virus disease. COVID19, virus identified

Interventions

Intervention 1: Intervention group: The extracted tooth is brought to the laboratory. After separating the tooth pulp, it is digested enzymatically and cultured. Once the cells have reached a sufficie

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18-95 years Patients Approved for Covirus 19 by Laboratory Methods Patients with mild to moderate respiratory distress Hospitalization in the ICU

Exclusion criteria

Exclusion criteria: Patients undergoing other clinical trials Patients with underlying diseases including diabetes, heart disease, respiratory disease, cancer patients and patients undergoing chemotherapy.

Design outcomes

Primary

MeasureTime frame
Pulmonary Condition. Timepoint: At the beginning of the study and 1 day and 2 days, 4 days, 7 days and 14 days after the start of the study. Method of measurement: CT scan.;Expression of nucleic acid of virus. Timepoint: At the beginning of the study and 1 day and 2 days, 4 days, 7 days and 14 days after the start of the study. Method of measurement: real time PCR.;Lymphocytes count. Timepoint: At the beginning of the study and 1 day and 2 days, 4 days, 7 days and 14 days after the start of the study. Method of measurement: Flowcytometry.;Patients clinical signs. Timepoint: At the beginning of the study and 1 day and 2 days, 4 days, 7 days and 14 days after the start of the study. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Farsinejad

Kerman University of Medical Sciences

afarsinejad@kmu.ac.ir+98 34 3132 5374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026