Radio protective effect of royal jelly against ionizing-radiation

Determination of radio protective effect of Royal Jelly on ionizing radiation-induced DNA damage in human peripheral blood lymphocytes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014090819091N1

Enrollment

Registered

2014-09-13

Start date

2015-02-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Male infertility. Condition 2: Radiation exposure. Condition 3: Ionizing radiation exposure. Male infertility Exposure to radiation Exposure to ionizing radiation

Interventions

This is an quasi-experimental study just including intervention group. In this study each participant gives blood samples twice. First sampling, on admission to the fertility center. After first sampl

Prevention

Eligibility

Sex/Gender

Male

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: men; at the age of 20 to 45 year old; Exclusion criteria: having a history of cancer; autoimmune diseases; having allergy to bee sting, to honey, to royal jelly and pollen; having a history of smoking; radiotherapy; chemotherapy; nuclear medicine scan; antibiotic therapy during last three months before attending the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Lymphocyte DNA tail length. Timepoint: A)On admission B)Two weeks after oral administration of royal jelly. Method of measurement: Visual scoring of DNA tail.	—

Secondary

Measure	Time frame
Sperm count in semen sample. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: Hemocytometer.;Gamma radiation dose. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: in Gy scale measured by gamma radiation dosimeter.;Sperm morphology in semen sample. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: Hemocytometer.;Sperm motility in semen sample. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: Hemocytometer.	—

Measure

Time frame

Sperm count in semen sample. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: Hemocytometer.;Gamma radiation dose. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: in Gy scale measured by gamma radiation dosimeter.;Sperm morphology in semen sample. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: Hemocytometer.;Sperm motility in semen sample. Timepoint: A)On admission B)75 days after oral administration of royal jelly. Method of measurement: Hemocytometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Shabestani Monfared

Babol university of medical sciences

monfared_ali@yahoo.commonfared1345@gmail.com+98 11 3528 9256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026