Hashimoto’s Thyroiditis. Autoimmune thyroiditis
Conditions
Interventions
Intervention 1: Nigella sativa group will receive 2 gram of Nigella sativa powder in the form of 1 gram packs with lunch and dinner meals for 8 weeks.The supplement will be given weekly and during the
Treatment - Drugs
Placebo
Nigella sativa group will receive 2 gram of Nigella sativa powder in the form of 1 gram packs with lunch and dinner meals for 8 weeks.The supplement will be given weekly and during the consumption pos
Placebo group will receive 2 gram of starch in the form of 1-gram packs with lunch and dinner meals weekly for 8 weeks and during the consumption possible side effects and keeping on consumption will
Sponsors
Vice chancellor for Research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Age Range of 20-50; Suffering from Hashimoto disease with the Diagnosis of Physician based on specialized Tests; Completing Informed Consent Form. Exclusion Criteria: not signed informed consent Form; physiologic Special conditions such as pregnancy and breast-feeding; receiving supplements such as Vitamin E, C, Zinc, Folat, Cobalamin, Soy fitoestrogens in the last 3 month; suffering from any auotoimmune disease; history of thyroid operation, following any special diet
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum concentration ofIL-23. Timepoint: At baseline and after 2 months of intervention. Method of measurement: ELISA.;Serum concentration ofTGF-ß. Timepoint: At baseline and after 2 months of intervention. Method of measurement: ELISA.;Serum concentration ofT4, T3? TSH?TPOAb. Timepoint: At baseline and after 2 months of intervention. Method of measurement: ELISA.;Serum concentration ofT4, T3? TSH?TPOAb. Timepoint: At baseline and after 2 months of intervention. Method of measurement: ELISA.;Added at 2017-02-12: Serum Concentrations of MDA, GPX, SOD and TAC. Timepoint: Added at 2017-02-12: Before and after intervention. Method of measurement: Added at 2017-02-12: ELIZA.;Added at 2017-02-12: Serum TAC. Timepoint: Added at 2017-02-12: At baseline and after 2 months of intervention. Method of measurement: Added at 2017-02-12: ELIZA.;Added at 2017-02-12: Serum CAT. Timepoint: Added at 2017-02-12: At baseline and after 2 months of intervention. Method of measurement: Added at 2017-02-12: ELIZA.;Added at 2017-02-12: Serum GPX. Timepoint: Added at 2017-02-12: At baseline and after 2 months of intervention. Method of measurement: Added at 2017-02-12: ELIZA.;Added at 2017-02-12: Serum SOD. Timepoint: Added at 2017-02-12: At baseline and after 2 months of intervention. Method of measurement: Added at 2017-02-12: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical Activity. Timepoint: At baseline and after 2 months of intervention. Method of measurement: Physical Activity Questionare.;Receiving Energy and Macronutrients. Timepoint: Before The first month termination and after the eight week. Method of measurement: 24-hour memorial questionare.;BMI. Timepoint: At baseline and after 2 months of intervention. Method of measurement: Weight divided by Height Square. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSirus Tajmiri
Tabriz University of Medical Sciences
Outcome results
None listed