healthy obese volunteer. Simple obesity NOS
Conditions
Interventions
Intervention 1: The intervention group will prescribe DASH diet that is rich in fruits, vegetables, whole grains, and low fat dairy products, and low in saturated fat, total fat, cholesterol, refined
Lifestyle
The intervention group will prescribe DASH diet that is rich in fruits, vegetables, whole grains, and low fat dairy products, and low in saturated fat, total fat, cholesterol, refined grains and swee
The control group was recommended to “eat as usual” and received healthy dietary advises which would be printed on a paper .Every participant will bring his 3-day diet records every month, and the da
Sponsors
Isfahan University of Medica Science ,Deputy Director of Research and Development
Eligibility
Sex/Gender
Female
Age
20 Years to 49 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: female; Body Mass Index above 30; age 20-50; absence of cardiovascular; hepatic; renal; thyroid; diabetes; rheumatoid arthritis; lupus; severe infection; trauma; allergy disease; don't use of multivitamin and mineral or omega-3 fatty acids supplements; don't regular use of antacid drugs containing magnesium and calcium ; consumption Aspirin and Non Steroid Anti Inflammation; and anti-depressant and hormone drugs; lack of pregnancy and breastfeeding; don't get weight loss in 6 months (more than 1 kg; don't use of tobacco and alcohol. Exclusion criteria: Failure to follow the prescribed diet( energy intake is different more than 300 calorie from prescribed as regard to food record analysis ), if weight change is more than 5%, diagnosis one of mentioned disease in inclusion criteria and using of chemical or herbal medicines during the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PPAR gamma Gene Expression. Timepoint: Before Intervention and After 3 Months. Method of measurement: Real Time Polymerase Chain Reaction.;IRS1 Gene Expression. Timepoint: Before Intervention and After 3 Months. Method of measurement: Real Time Polymerase Chain Reaction.;Insulin resistance. Timepoint: Before Intervention and After 3 Months. Method of measurement: Hemostatic Model Assessment(HOMA). | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Before Study and After 3 Months. Method of measurement: Scale.;Fasting Sugar. Timepoint: Before Study and After 3 Months. Method of measurement: Caloremetric.;Fasting Insulin. Timepoint: Before Study and After 3 Month. Method of measurement: Elisa Method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohammad Hasan Entezari
Isfahan University of Medical Science
Outcome results
None listed