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Comparative evaluation of the effect of two different fluid therapy regimen on the bowel motility return after surgery

Comparative evaluation of the effect of two different fluid therapy regimen (crystalloid VS crystalloid + colloid) on the speed of bowel motility return after gastrointestinal resection & anastomosis surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014090711398N7
Enrollment
100
Registered
2014-11-30
Start date
2013-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ileus. Paralytic ileus

Interventions

Intervention 1: Intervention group: For the fluid therapy of the patients of this group, we will use a combination of crystalloid & colloid fluids. Where, colloid will be used to replace the third spa
Treatment - Other
Treatment - Drugs
Intervention group: For the fluid therapy of the patients of this group, we will use a combination of crystalloid & colloid fluids. Where, colloid will be used to replace the third space loss and blee
In control group:Total calculated fluid need of patients will be replaced with crystalloid (normal saline & ringer lactate in 50:50 ratio)

Sponsors

Research Deputy of Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients candidated for resection & anastomosis of gastrointestinal surgery; Age between 18 - 60 years old; Patients with ASA physical status class I-III; Having consent for entry. Exclusion criteria: Age less than 18 & more than 60; Patients with ASA physical status over than III; Pregnant females; Patients with acute or chronic uncompensated cardiac insufficiency; Known coagulopathy; Hepatic insufficiency ( 2-3 times increase in liver enzymes); Renal insufficiency ( more than 50% rise in creatinine); Known gastroparesis & bowel motility disorders; Fatty patients with BMI over than 35

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ileus. Timepoint: Day after intervention. Method of measurement: Based on questionnare.

Secondary

MeasureTime frame
Nausea & Vomiting. Timepoint: Day after intervention. Method of measurement: Based on questionnaire.;Anastomosis leak. Timepoint: Day after intervention. Method of measurement: Based on clinical chart documents.;Dehiscence. Timepoint: From day after intervention. Method of measurement: Based on clinical observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosein Reza Dehghan MD.

Iran University of Medical Sciences

dhoseinreza@gmail.com+98 21 8894 6762

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026