Knee osteoarthritis. Osteoarthritis of knee
Conditions
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Diagnosis of primary knee osteoarthritis, grades 2 and 3, confirmed by a physician based on Kellgren and Lawrence criteria (presence of knee pain, morning stiffness lasting less than 30 minutes, crepitus during movement, and radiographic signs of osteoarthritis including joint space narrowing, subchondral bone sclerosis, and osteophyte formation in the knee). Age between 45 and 70 years. Presence of persistent knee pain for at least six months, with a minimum severity of 4 on the Visual Analog Scale (VAS) during activities such as climbing stairs, prolonged sitting, and squatting. Ability to walk independently for at least 30 meters. Body Mass Index (BMI) equal to or less than 35. Full informed consent from the patient to participate in the study. Stable and balanced mental/psychological state.
Exclusion criteria
Exclusion criteria: History of intra-articular injection in the knee within the past six months. Diagnosis of neuromuscular diseases. Presence of acute traumatic injury to other ligaments and structures of the knee joint, as confirmed by a specialist physician. History of surgery or previous lesions in the knee or other lower limb joints within the past year. Presence of bone implants. Occurrence of a new fracture in the lower limb within the past year. Diagnosis of malignant tumors. Participation in sports therapy or physiotherapy programs within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feeling knee pain by Visual Analogue Scale (VAS). Timepoint: The time of follow-up of patients is zero months (first visit), one, three and six months. Method of measurement: with the VAS questionnaire.;Knee function with WOMAC(Western Ontario and McMaster Universities Osteoarthritis Index) scale. Timepoint: The time of follow-up of patients is zero months (first visit), one, three and six months. Method of measurement: with WOMAC questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee range of motion. Timepoint: The time of examination of patients is in zero months (initial visit), one, three and six months. Method of measurement: Goniometry.;Timed Up & Go test: The ability of a person to get up from a chair over a distance of 3 meters and return to the chair. Timepoint: The time of examination of patients is in zero months (initial visit), one, three and six months. Method of measurement: Stopwatch (seconds).;Six Minute Walk test: The person's ability to walk for 6 minutes. Timepoint: The time of examination of patients is in zero months (initial visit), one, three and six months. Method of measurement: Distance measurement (meter).;Stair climbing test: The ability of a person to climb stairs to reach the stage of pain or fatigue. Timepoint: The time of examination of patients is in zero months (initial visit), one, three and six months. Method of measurement: The number of steps taken. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Mazaherinezhad
Iran University of Medical Sciences
Outcome results
None listed