Knee Osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: First Intervention group:First intervention group: Preparation of PRP solution and injection will be done in sports medicine clinic of Hazrat Rasool Akram Hospital. The patients of bot
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: Grade 2 and 3 of primary knee osteoarthritis acording to KL criteria Age 50-75 year Persistent knee pain for at least 6 months with intensity more than 4 according to VAS in activity such as going up and down stair, long period of sitting and squatting Ability to walk independently for more than 30 m. BMI below 35 kg/m2 The patient has full consent to participate in the research. The patient should have a balanced mental state.
Exclusion criteria
Exclusion criteria: The patient has a history of intra-articular injection in the knee during the last six months. The patient has neuromuscular diseases. The patient has a history of acute traumatic injury to other ligaments and structures of the knee joint with the approval of a specialist. The patient has a history of surgery or previous injury in the knee and other lower limb joints over the last year. The patient has bone implants. The patient has a new fracture in the lower extremities during the last year. The patient has malignant tumors. The patient has participated in exercise therapy and physiotherapy programs during the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee function with WOMAC(Western Ontario and McMaster Universities Osteoarthritis Index) scale. Timepoint: Before the intervention and one month and three months after the intervention. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index questionnaire.;Feeling knee pain by Visual Analogue Scale (VAS). Timepoint: Before the intervention and one month and three months after the intervention. Method of measurement: Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee range of motion. Timepoint: Before the intervention, one month and three months after the intervention. Method of measurement: Goniometry.;Timed Up & Go test: The ability of a person to get up from a chair over a distance of 3 meters and return to the chair. Timepoint: Before the intervention, one month and three months after the intervention. Method of measurement: Stopwatch (seconds).;Six Minute Walk test: The person's ability to walk for 6 minutes. Timepoint: Before the intervention, one month and three months after the intervention. Method of measurement: Distance measurement (meter).;Stair climbing test: The ability of a person to climb stairs to reach the stage of pain or fatigue. Timepoint: Before the intervention, one month and three months after the intervention. Method of measurement: The number of steps taken. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Mazaherinezhad
Iran University of Medical Sciences
Outcome results
None listed