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Analgesic effect of Lidocaine-ketorolac versus lidocaine-dexmedetomidine for intravenous regional anesthesia

Analgesic effect of Lidocaine-ketorolac versus lidocaine-dexmedetomidine for intravenous regional anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014090614056N3
Enrollment
90
Registered
2014-09-23
Start date
2013-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regional anesthesia. Local anaesthetics

Interventions

Intervention 1: Intervention:2 groups which one of them will take 3 mg/kg lidocaine 0.5% with 1 µg/kg dexmedetomidine dilutioned by saline0.9% to 40 cc.next group will take 3 mg/kg lidocaine 0.5% wit
Treatment - Drugs
Intervention:2 groups which one of them will take 3 mg/kg lidocaine 0.5% with 1 µg/kg dexmedetomidine dilutioned by saline0.9% to 40 cc.next group will take 3 mg/kg lidocaine 0.5% with 30mg ketrolac
control:these patients will take 3 mg/kg lidocaine 0.5% dilutioned by saline 0.9% to 40 cc in 90 seconds.

Sponsors

Arak University of Medical Sciences, Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 20 to 50 years old; ASA I or II. Exclusion criteria: drug allergy history; history of cardiac disease; hypertension treated with methyl dopa and clonidine; bradycardia; pregnancy; hematologic disorders and coagulopathies; renal diseases; gastrointestinal bleeding; operation duration lesser than 40 and over 90 minutes; opiate or analgesic drugs history.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Tourniquet pain. Timepoint: After injection then 15, 30 and 45 minute after injection. Method of measurement: VAS.

Secondary

MeasureTime frame
Reduction of pain. Timepoint: Every 30 minutes until 2 hours after removing tourniquet. Method of measurement: VAS.;Vital signs. Timepoint: After removing tourniquet. Method of measurement: Common ways.;O2 saturation. Timepoint: After removing tourniquet. Method of measurement: Pulse oxymeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHesameddin Modir

Vali-e-Asr hospital

he_modir@arakmu.ac.ir+98 86 3223 1104

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026