Skip to content

The effect of anesthetic agents on tracheal tube cuff pressure

Comparison of the effect of Pofoll, Isoflurane and Nitric oxide on endotracheal tube cuff pressure in patients undergoing elective surgery with general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014090412642N4
Enrollment
136
Registered
2014-10-04
Start date
2014-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tracheal intubation. Unspecified adverse effect of drug or medicament

Interventions

Intervention 1: (group A) use of intravenous hypnotic anesthetic (propofol) with dosage of 150ug/kg/min have received in during general anesthesia. Intervention 2: (group B) use of volatile anestheti
Early detection
(group A) use of intravenous hypnotic anesthetic (propofol) with dosage of 150ug/kg/min have received in during general anesthesia
(group B) use of volatile anesthetic (isofluranl) 1% in during general anesthesia
(group C) use of Patients in the intravenous hypnotic anesthetic (propofol) with dosage of 150ug/kg/min with N2o ratio 50-50 in general anesthesia
(group D) use of volatile anesthtic(isofluran) 1% with N2O ratio 50-50in general anesthesia

Sponsors

Vice Chancellor of Research of Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: Patients undergoing elective surgery; ASA class I and II exclusion criteria: Patients outside the age range 15 to 65 years; patients with a high ASA class II; patients with systemic disease heart- lung, renal endocrine or metabolic; morbid obesity (BMI>40); Surgical practice time for less than 1.5 hour; positions other than supine; head and neck and thoracic surgery; neck rotation during surgery more than 10 degrees; Endotracheal tube cuff pressure increases to more than 40 cmH2o during anesthesia; difficult intubation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Tracheal cuff pressure. Timepoint: Before the experiment and then every 30 minutes. Method of measurement: In millimeters of mercury using a cuff pressure manometer.

Secondary

MeasureTime frame
Blood pressure. Timepoint: end of study. Method of measurement: Manometer to measure the pressure.;Heart rate. Timepoint: end of study. Method of measurement: with pulse oxymetry.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026