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Effect of Sodium Bicarbonate Buffered Lidocaine 2% in the treatment of teeth with acute pain

Effect of Sodium Bicarbonate Buffered Lidocaine 2% on the Success of Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014090219021N1
Enrollment
80
Registered
2014-09-13
Start date
2014-09-13
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis. Pulpitis

Interventions

Intervention 1: patients will divided into two groups. 2 inferior alveolar nerve block with 2 similar cartridges will be injectet to each patient. . Endodontic access preparation will be begun 15 minu
Septodont, Saint Maur des Fosses, France) with 1:80,000 epinephrine with 0.3 mL sterile distilled water. Intervention 2: patients will divided into two groups. 2 inferior alveolar nerve block with 2 s
Septodont, Saint Maur des Fosses, France) buffered with 0.3 mL of 8.4% sodium bicarbonate (8.4% weight/volume, 50 mEq/50 mL, Samen Laboratories, Iran).
Treatment - Drugs
patients will divided into two groups. 2 inferior alveolar nerve block with 2 similar cartridges will be injectet to each patient. . Endodontic access preparation will be begun 15 minutes after inject
Septodont, Saint Maur des Fosses, France) with 1:80,000 epinephrine with 0.3 mL sterile distilled water

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: age 20-60 years; no history of systemic diseases; lower molars with symptomatic irreversible pulpitis exclusion criteria: active sites of pathosis in the area of injection; Lack of lip numbness within 15 minutes after injection

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Degree of initial pain. Timepoint: before root canal therapy. Method of measurement: visual analogous scale.

Secondary

MeasureTime frame
Degree of Secondary pain. Timepoint: during root canal therapy. Method of measurement: visual analogous scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Badri Baghaei

Isfahan University of Medical Sciences

f-rajati@hlth.mui.ac.irbadribaghaie@gmail.com+98 31 3792 2886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026