migraine. Migraine without aura [common migraine]Migraine with aura [classical migraine]
Conditions
Interventions
Intervention 1: control group will receive common treatment for migraine prophylaxis. Intervention 2: intervention group will use CoQ10 for six months in addition to their traditional medicines. COQ10
Treatment - Drugs
control group will receive common treatment for migraine prophylaxis
intervention group will use CoQ10 for six months in addition to their traditional medicines. COQ10 will prescribe with a dose of 100 mg per day orally
Sponsors
Research Department of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: inclusion criteria: A definitive diagnosis of migraine based on IHS criteria; having at least one headache per week or 4 per month or having less frequent attacks providing that there is another indication for prophylactic treatment such as suffering from long-lasting disabling attacks; signing informed consent forms by the patient .Exclusion criteria: Having another serious disease such as diabetes, hypertension, thyroid disease, or asthma that interferes with migraine or its preventive treatment; using COQ10 during the last month before study involvement by the patient for another reason; consuming drugs with potential effects of aggravating migraine attacks such as OCP, nitrate compounds, vasodilatators, ...; failure to follow-up the patient for 6 months.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache. Timepoint: 1,3,6 months. Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Associated symptoms of Migraine. Timepoint: 1.3.6 month. Method of measurement: Questionnaires and Interview. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohsen Soltani
Mashhad University of Medical Sciences
Outcome results
None listed