Evaluation of the effects of preoperative administration of oral pregabalin on postoperative pain

The effects of preoperative administration of oral pregabalin on postoperative pain after abdominal surgeries

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201408272963N19

Enrollment

Registered

2014-12-26

Start date

2014-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pregabalin. Other and unspecified antiepileptics

Interventions

placebo at the same time

Intervention 1: pregabalin 300 mg orally 2 hours before surgery. Intervention 2: placebo at the same time.

Treatment - Drugs

Placebo

pregabalin 300 mg orally 2 hours before surgery

Eligibility

Sex/Gender

Female

Age

40 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: women with American Society of Anesthesia (ASA) physical status I or II who are candidate for elective abdominal surgery, age 40-60 years old, BMI<35. Exclusion criteria: Anaphylaxis reaction to the anesthetic drugs, duration of the operation longer than 2 hours

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Postoperative pain. Timepoint: 2,6,12,24 hours postoperatively. Method of measurement: visual analog pain score.	—

Secondary

Measure	Time frame
Side effects of pregabalin (dizziness, blured vision, ataxia, nausea, vomitting). Timepoint: 2, 6, 12 and 24 hours after operation. Method of measurement: asking the patient, physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Shekoufeh Behdad

Shahid Sadoughi University of Medical Sciences

behdad90@gmail.com+98 35 3822 4104

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026