Idiopathic hirsutism. Hirsutism
Conditions
Interventions
Intervention 1: Intervention group: Licorice gel used twice a day on one side face for 24 months. Intervention 2: Control group: Placebo gel used twice a day on face one side face for 24 months. Inter
Treatment - Drugs
Placebo
Treatment - Other
Intervention group: Licorice gel used twice a day on one side face for 24 months.
Control group: Placebo gel used twice a day on face one side face for 24 months
Intervention and control groups: Five sessions at six weeks intervals of alexandrite laser (fluency: 14-20 mill joule and pulse width: 35-40 millisecond)
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Female with regular menses and normal androgen level; Age between 15 and 45 years; Skin phototype II to IV; Mild to moderate idiopathic hirsutism on both sides of the face. Exclusion criteria: Pregnancy or intention to become pregnant; Increased level of androgens; Irregularity of menses; Sever form of hirsutism; Use of effective medication on hirsutism in the last two months; Androgens or anti-androgen and oral contraceptive agents intake within the previous two months; Allergy or hypersensitivity to any components of the product under investigation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of terminal hairs. Timepoint: At base line and end of study. Method of measurement: Photography and manual counting. | — |
Secondary
| Measure | Time frame |
|---|---|
| Local tolerance to topical gel. Timepoint: One and three days after initial topical gel administration and every four weeks. Method of measurement: Clinical evaluation.;Local tolerance to laser. Timepoint: One and three days after each session. Method of measurement: Clinical evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Bhar Saffar
Isfahan University of Medical Sciences
Outcome results
None listed