Blood Cancer. Autologues Transplantation Patients. Multiple myeloma
Conditions
Interventions
Intervention 1: Intervention group: Continuous and discontinuous aerobic exercise during 7 days of mobilization plus routine treatment of stimulation bone marrow pre-transplantation with a sample size
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
19 Years to 65 Years
Inclusion criteria
Inclusion criteria: Diagnosis of leukemia(Multiple myeloma and Hodgkin lymphoma) based on cellular pathology Patients Candidate for Autologous Stem Cell Transplantation as Cancer Treatment Written and informed consent from the subjects under study Age between 19 to 60 years Proper Functional Status of the Patient for doing Exercises (Functional Status Based on Karnowski criteria above 9) Absence of chronic comorbidities such as hypertension, heart disease, respiratory and allergic diseases, diabetes and kidney failure... No orthopedic problems that prevent the exercise Mobilization with a single drug and with the same injection method
Exclusion criteria
Exclusion criteria: Patient request and desire to exclude the study Discontinuation of continuous aerobic exercise more than one consecutive session. Discontinuation of interval aerobic exercise for more than one consecutive session. Failure to perform at least 7 continuous aerobic training sessions daily during the mobilization period. Failure to perform at least 7 discontinuous aerobic training sessions daily during the mobilization period. Hemoglobin drop below 8. Decreased platelet count of the patient to below 50,000 Indication of fever and neutropenia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD34 and MNC cells count for transplant. Timepoint: Before mobilization and after 1 week standard pre-transplant treatment plus exercise( intervention group) Before mobilization and after 1 week standard pre-transplant treatment without exercise(control group). Method of measurement: the number of mononuclear and CD34 cells by the report of pathologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital admission length after transplant. Timepoint: after patients discharge. Method of measurement: admition days based on the hospital documentation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKimia Kasravi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed