The effect of general and epidural anesthesia on respiratory parameters during and after laparoscopic cholecystectomy surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014081714333N19

Enrollment

Registered

2014-09-07

Start date

2014-06-15

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparascopic cholecystectomy. Cholecystolithiasis

Interventions

Intervention 1: In the first group(GA), After pre-medication among GA with midazolam 05.0 mg/kg, intravenous fentalyn 1 µg/kg, patients are anesthetized using propofol 2 mg/kg and atracurium 5.0 mg/

Treatment - Surgery

In the first group(GA), After pre-medication among GA with midazolam 05.0 mg/kg, intravenous fentalyn 1 µg/kg, patients are anesthetized using propofol 2 mg/kg and atracurium 5.0 mg/kg and standard

In the second group (EA), 10 cc Lidocaine and epinephrine 1 in 200000, including 1 cc sodium bicarnonate for each 10 cc of Lidocaine, would be injected in the space between vertebrae of the thoracic u

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Entrance criteria includes written consent by patients; I, II ASA class; age range of 20 to 60; no history on respiratory or cardio problems; no history on diabetes or similar diseases needing treatment. Exclusion criterion is a surgery lasting more than 45 minutes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
FEV1. Timepoint: A day before and after surgery. Method of measurement: Using spirometry.;VC. Timepoint: During and an hour after surgery. Method of measurement: Using anesthesia machine monitor.;SPO2. Timepoint: Before, during and an hour after surgery. Method of measurement: Using pulse oxy meter monitor.;PH. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;Pao2. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;PaCo2. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;Hco3. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;FVC. Timepoint: A day before and after surgery. Method of measurement: Through spirometry.;O2SAT. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).	—

Measure

Time frame

FEV1. Timepoint: A day before and after surgery. Method of measurement: Using spirometry.;VC. Timepoint: During and an hour after surgery. Method of measurement: Using anesthesia machine monitor.;SPO2. Timepoint: Before, during and an hour after surgery. Method of measurement: Using pulse oxy meter monitor.;PH. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;Pao2. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;PaCo2. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;Hco3. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).;FVC. Timepoint: A day before and after surgery. Method of measurement: Through spirometry.;O2SAT. Timepoint: Before, during and an hour after surgery. Method of measurement: Using blood gas analysis (ABG).

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Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026