Evaluation of the effect of antibiotic prophylaxis in implant surgery with guided bone regeneration.

Evaluation of the effect of antibiotic prophylaxis on clinical and patient reported outcome and inflammation-related indicators of oral implant therapy with guided bone regeneration.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140817018834N8

Enrollment

100

Registered

2021-06-10

Start date

2021-06-13

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Horizontal alveolar bone defects.. Atrophy of edentulous alveolar ridge

Interventions

Intervention 1: Intervention group: In patients who are candidates for implant placement, the guided bone regeneration treatment will be performed using one type of membrane and one type of bone graf

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: • An age range of 20 to 50 years • The extent of the lesion (horizontal bone augmentation) is about one or two teeth • No previous surgical procedures have been initiated in the specific area • The patient's informed consent •Absence of systemic diseases that interfere healing process, such as diabetes • Non smoker •Do not take drugs interfere with the treatment process, such as corticosteroids • Dehiscence defects in buccal surface of the implant

Exclusion criteria

Exclusion criteria: • Do not refer for routine follow up visits • Patients who are allergic to amoxicillin • The presence of severe infection in the oral cavity • Wound opening during bone transplantation surgery

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1-3-7 days after surgery. Method of measurement: The patient is asked about the amount of pain by telephone using the visual analogue scale index on the first, third, and seventh days, and the patient is asked to rate their pain experience on a scale from 0 to 10 .;Swelling. Timepoint: 1_3_7 days after surgery. Method of measurement: On the first, third and seventh day, the patient is asked about the presence or absence of swelling. due to special conditions in COVID-19 prevalence and attracting patient involvement and cooperation, On the third day, the patient will be examined remotely by sending a full face photo.;Bleeding. Timepoint: 1_3_7 days after surgery. Method of measurement: On the first, third and seventh day, the patient is asked about the presence or absence of bleeding. due to special conditions in COVID-19 prevalence and attracting patient involvement and cooperation, On the third day, the patient will be examined remotely by sending a full face photo.;Hematoma. Timepoint: 1_3_7 days after surgery. Method of measurement: On the first, third and seventh day, the patient is asked about the presence or absence of hematoma. due to special conditions in COVID-19 prevalence and attracting patient involvement and cooperation, On the third day, the patient will be examined remotely by sending a full face photo.	—

Measure

Time frame

Pain. Timepoint: 1-3-7 days after surgery. Method of measurement: The patient is asked about the amount of pain by telephone using the visual analogue scale index on the first, third, and seventh days, and the patient is asked to rate their pain experience on a scale from 0 to 10 .;Swelling. Timepoint: 1_3_7 days after surgery. Method of measurement: On the first, third and seventh day, the patient is asked about the presence or absence of swelling. due to special conditions in COVID-19 prevalence and attracting patient involvement and cooperation, On the third day, the patient will be examined remotely by sending a full face photo.;Bleeding. Timepoint: 1_3_7 days after surgery. Method of measurement: On the first, third and seventh day, the patient is asked about the presence or absence of bleeding. due to special conditions in COVID-19 prevalence and attracting patient involvement and cooperation, On the third day, the patient will be examined remotely by sending a full face photo.;Hematoma. Timepoint: 1_3_7 days after surgery. Method of measurement: On the first, third and seventh day, the patient is asked about the presence or absence of hematoma. due to special conditions in COVID-19 prevalence and attracting patient involvement and cooperation, On the third day, the patient will be examined remotely by sending a full face photo.

—

Secondary

Measure	Time frame
Implant survival. Timepoint: 3 months after surgery. Method of measurement: Clinical and radiography examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNahid Nasrabadi

Mashhad University of Medical Sciences

nasran@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026