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Investigating the anti-emetic effect of Rheum ribes L.

Investigating the anti-emetic effect of Rheum ribes L. aqueous extract on breast cancer patients receiving ACT chemotherapy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140817018828N6
Enrollment
56
Registered
2018-06-27
Start date
2016-07-22
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer. Malignant neoplasm of breast

Interventions

Intervention 1: Intervention group: aqueous extract of Rheum ribes L. , in 7 days, 5cc every day. Intervention 2: Control group: placebo, in 7 days, 5cc every day.

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with breast cancer Adriamycin, Cytoxan, Taxol (ACT) chemotherapy regimen The first or second course of chemotherapy Patient's satisfaction

Exclusion criteria

Exclusion criteria: Patients with other cancer history History of receiving chemotherapy History of seizure and use of anti-convulsant drugs Nausea and vomiting degree 2 or 3 within 24 hours prior to chemotherapy Persistent, moderate or severe nausea Hepatitis or gastrointestinal obstruction and metastasis

Design outcomes

Primary

MeasureTime frame
Severity of nausea. Timepoint: 8 days after receiving chemotherapy. Method of measurement: National Chemotherapy Institute (NCI) table of nausea grade.

Secondary

MeasureTime frame
Duration of nausea. Timepoint: 8 days after chemotherapy. Method of measurement: How many days have nausea.;Frequency of vomiting. Timepoint: 8 days after chemotherapy. Method of measurement: National Chemotherapy Institute (NCI) table of vomiting grade.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlimohammad RanjbarJamalabadi

Yazd University of Medical Sciences

amranjbar@razi.tums.ac.ir+98 35 3820 3865

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026