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Evaluation of Rheum ribes L. aqueous extract effect on neuropathy

Determination of Rheum ribes L. aqueous extract effect on FOLFOX-induced neuropathy in patients with Colorectal Cancer

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140817018828N4
Enrollment
44
Registered
2018-06-02
Start date
2016-09-22
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer. Malignant neoplasm of colon

Interventions

Intervention 1: Intervention group: Patients randomly enter the intervention group, and use 5 ml of the prescribed extract for 7 days from the second day of chemotherapy until the seventh course of ch

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with Colorectal Cancer aged between 20 and 80 years old receiving the FOLFOX chemotherapy regimen

Exclusion criteria

Exclusion criteria: patients with a history of other types of cancers history of receiving chemotherapy history of seizure and drug use anticonvulsants previous neuropathy having allergies and allergic to each of the components studied

Design outcomes

Primary

MeasureTime frame
. Peripheral neuropathy. Timepoint: End of day 7 after each chemotherapy course until the seventh term of chemotherapy. Method of measurement: questionnaire.

Secondary

MeasureTime frame
The sensitivity touching cold. Timepoint: End of day 7 after each chemotherapy course until the seventh term of chemotherapy. Method of measurement: questionnaire.;Hyperalgesia. Timepoint: End of day 7 after each chemotherapy course until the seventh term of chemotherapy. Method of measurement: questionnaire.;Experiencing tingling in hands or feet. Timepoint: End of day 7 after each chemotherapy course until the seventh term of chemotherapy. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlimohamad Ranjbar Jamal abadi

Yazd University of Medical Sciences

Amranjbar@razi.tums.ac.ir+98 35 3820 3865

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026