Comparison of the effect of oxygen and placebo in treatment of non ST elevation acute coronary syndrome

Comparison of the effect of oxygen and placebo on clinical outcomes in patients with non ST elevation acute coronary syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014081118768N1

Enrollment

Registered

2014-11-24

Start date

2014-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic heart diseases. ????? ????????? ????????? ??? ??????? ??? ????????

Interventions

Intervention 1: Intervention group: at 6 hours after arriving at the hospital, oxygen will be given at a rate of 4 to 6 liters per minute by nasal cannula. Intervention 2: Control group: at 6 hours af

Treatment - Drugs

Intervention group: at 6 hours after arriving at the hospital, oxygen will be given at a rate of 4 to 6 liters per minute by nasal cannula.

Control group: at 6 hours after arriving at the hospital, room air will be given at a rate of 4 to 6 liters per minute by nasal cannula.

Eligibility

Sex/Gender

All

Age

18 Years to 84 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 18-84 years; diagnosed with acute coronary syndrome with non ST segment elevation according to Branvald criteria; no clinical evidence of heart failure; no chronic lung disease or other respiratory problems; lack of cardiac arrest or cardiogenic shock before entering the hospital; oxygen saturation above 90% on admission; absence of congenital heart disease. Exclusion criteria: Need for inotropic support; having ST elevation acute myocardial infarction; oxygen saturation less than 90% during hospitalization; emergency coronary angioplasty or emergency coronary artery bypass during hospitalization; death.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cardiac dysrhythmias. Timepoint: Continues over 24 hours. Method of measurement: Cardiac monitoring device.;Chest pain. Timepoint: 24 - 28 - 32 - 36 - 40 - 44 - 48 hours. Method of measurement: check list, visual analogue scale.;The amount of narcotic analgesic. Timepoint: 48 hours. Method of measurement: check list.	—

Secondary

Measure	Time frame
Readmission due to cardiac problems. Timepoint: End of weeks 1- 2- 3- 4. Method of measurement: The phone call.;Visit due to cardiac problems. Timepoint: End of weeks 1- 2- 3- 4. Method of measurement: The phone call.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Heidari

Arak University of Medical Sciences

f.heidari@arakmu.ac.ir/mahboobeh63n@yahoo.com+98 77 1252 7971

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026