The Effect of Iranian Propolis on Radiation- Induced oral ulceration

The Effect of Iranian Propolis on Radiation- Induced Mucositis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014081018753N1

Enrollment

Registered

2015-01-23

Start date

2014-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucositis. Oral mucositis (ulcerative)

Interventions

Intervention 1: Prpolis , Tab 300 mg, oral, 8 times day , 6 weaks. Intervention 2: placebo( lactose),Tab 300 mg , 8 times a day ,six weaks.

Treatment - Drugs

Prpolis , Tab 300 mg, oral, 8 times day , 6 weaks

placebo( lactose),Tab 300 mg , 8 times a day ,six weaks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: oral cancer ; received dose of at least 4000 Gy ; being oral cavity in the field of radiation. Exclusive criteria are: presence of any systemic diseases such as diabetes , hypertension ; oral active infection ; active collagen vascular disease ; smoking ; presence of any type of allergy ; sensitivity to honey and its products ; history of radiation therapy to the head and neck area ; receiving chemotherapy at the same time ; stopping the radiation because of severe mucositits.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mucositis severity. Timepoint: weekly. Method of measurement: By OMAS & WHO indices.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFateme Sayyadi

Babol University of Medical Sciences

f.sayyadi90@yahoo.com+98 11 3230 0370

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026