Condition 1: Polycystic ovarian syndrome. Condition 2: Infertility. Sclerocystic ovary syndromeStein-Leventhal syndrome In vitro fertilization
Conditions
Interventions
Intervention 1: placebo of vit E once daily for 2 months. Intervention 2: pearl vit D,Biweekly for 2 months. Intervention 3: placebo of vit D,biweekly for 2 months. Intervention 4: pearl vit E,400 IU
Treatment - Drugs
placebo of vit E once daily for 2 months
pearl vit D,Biweekly for 2 months
placebo of vit D,biweekly for 2 months
pearl vit E,400 IU,once daily for 2 months
Sponsors
Avicenna Infertility Clinic
Eligibility
Sex/Gender
Female
Age
18 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: PCOS patients based on ROTERDOM criteria; age:18-38 years old; day3 FSH level less than 12; BMI:20-34. Exclusion criteria: patients with heart, liver or renal disease; patients with Endometriosis; use of anticoagulats: ASA, Heparin, Warfarin; use of antidepresants:Fluoxetin, Certeralin; use of Statins: Levastatin, Atorvastatin; patients with Eye disease: Retinitis pigmentosa; use of anti inflammatory drugs and corticosteroids:prednisolon; use of vitamins and anti oxidants in 3 months ago; vit K deficiency and bleeding disorders; history of chemotherapy or radiotherapy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum malondealdehyde. Timepoint: before intervention and after intervention on the oocyte collection day. Method of measurement: American key man kit.;Serum total antioxidant capaity(TAC). Timepoint: before intervention and after intervention on the oocyte collection day. Method of measurement: American key man kit.;Serum super oxid dismuthase. Timepoint: before intervention and after intervention on the oocyte collection day. Method of measurement: American key man kit.;Follicular fluid malondealdehyde. Timepoint: on the oocyte collection day. Method of measurement: American key man kit.;Follicular fluid total anti oxidant capacity. Timepoint: on the oocyte collection day. Method of measurement: American key man kit.;Follicular fluid super oxid dismuthase. Timepoint: on the oocyte collection day. Method of measurement: American key man kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oocyte quality. Timepoint: on the day of oocyte collection. Method of measurement: morphologic assesment with microscope.;ICSI outcome. Timepoint: 2 weeks after embryo transfer. Method of measurement: serum BHCG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farnaz Fatemi
Avicenna Infertility Clinic
Outcome results
None listed