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Therapeutic effects of Zataria Multiflora Essential Oil on recurrent oral aphthous lesions

Therapeutic effects of Zataria Multiflora Essential Oil on recurrent oral aphthous lesions

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201408076926N2
Enrollment
28
Registered
2014-08-28
Start date
2012-05-28
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent oral aphthous lesions. Recurrent oral aphthae

Interventions

Intervention 1: in intervention group:a bottle of 0.5% ZM essential oil. Intervention 2: interventon in control group: a bottle of placebo (distilled water with a cap scented with ZM essential oil).
Treatment - Drugs
Placebo
in intervention group:a bottle of 0.5% ZM essential oil
interventon in control group: a bottle of placebo (distilled water with a cap scented with ZM essential oil)

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were as follows: 1) Presence of a minor solitary aphthous lesion in labial or buccal epithelium. 2) No usage of other treatments for aphthous lesions. 3) No reduction in pain, pain intensity or burning sensation at the time of admission compared to the first days of occurrence of the lesion. 4) Willingness to participate in the study. 5) Age between 18 and 40 years old. Patients were excluded from the study: with any systemic diseases; pregnant patients; those with aphthous lesions older than 4 days and those who declined entering the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Recurrent oral aphthous lesion. Timepoint: Days: 0, 5, 7 and 10. Method of measurement: The healing time, pain intensity and aphthous zone diameter.

Secondary

MeasureTime frame
Pain. Timepoint: Days: 0, 5, 7 and 10. Method of measurement: Visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShaghayegh Nooribayat

Dental faculty, Babol University of Medical Sciences

sh.nooribayat@mubabol.ac.ir; Dr.sh.noori@gmail.com+98 11 4425 8603

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026