Respiratory distress of newborn. Respiratory distress of newborn, unspecified
Conditions
Interventions
Intervention 1: participants take 200 mg/kg surfactant by MIST method. Intervention 2: participants take 200 mg/kg surfactant by INSUR method.
Treatment - Drugs
participants take 200 mg/kg surfactant by MIST method
participants take 200 mg/kg surfactant by INSUR method
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 1 Months
Inclusion criteria
Inclusion criteria: Inclusion criteria: preterm neonates with 34 week age or less; respiratory distress due to surfactant deficiency; Exclusion criteria: parents have not consent with incorporating in study; neonate with asphyxia; neonates with intubation from the birth; respiratory distress not due to RDS; neonates with maternal abnormality
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Need for second dose surfactant. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.;Apnea. Timepoint: During hospitalization. Method of measurement: Visit.;Duration of Oxygen Consumption. Timepoint: Per 6 hour after intervention. Method of measurement: Chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications of surfactant injection (Coughing or Gagging, Pneumothorax, Surfactant Reflux, Bradycardia, Pulmonary Hemorrhage, Intra ventricular Hemorrhage (>grade 2)). Timepoint: Per 6 hour after intervention. Method of measurement: Chart and visit.;The rate of intubated in First 72 h of Life. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.;Length of Stay in NICU. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.;Death. Timepoint: During hospitalization. Method of measurement: Chart. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZohreh Farsi
Tehran University of Medical Sciences (Arash hospital)
Outcome results
None listed