Comparing the effect of Loading Doses of Clopidogrel and Prasugrel on the incidence of myocardial injury in the Candidates for Elective Percutaneous Coronary Intervention

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201408069768N3

Enrollment

Registered

2014-08-19

Start date

2013-01-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subsequent myocardial infarction. For morbidity coding, this category should be assigned for infarction of any myocardial site, occurring within 4 weeks (28 days) from onset of a previous infarction

Interventions

Intervention 1: Prasugrel (60 mg P.O. stat). Intervention 2: Plavix (600 mg P.O. stat).

Treatment - Drugs

Prasugrel (60 mg P.O. stat)

Plavix (600 mg P.O. stat)

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: we enrolled patients with stable angina who were candidate for elective PCI and gave informed consent to take part in this trial. The exclusion criteria included: history of coronary artery bypass graft surgery; need for emergency PCI (in less than 2 hours); history of renal dysfunction; any contraindication for prasugrel or Plavix; body weight1.5mg/dl; and ejection fraction<30%.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Periprocedural myocardial infarction. Timepoint: elevation of cTn values (>5 times) in patients with normal baseline values or a rise of cTn values >20% if the baseline values are elevated. Method of measurement: Blood survey.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkbar Shafiee

Tehran Heart Center

leo71538@yahoo.com+98 21 8802 9600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026