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effect of dexamethasone on dental pulp

Histologic response of human dental pulp to dexamethasone treatment following MTA-direct pulp capping and MTA-partial pulpotomy: A randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014080618711N1
Enrollment
40
Registered
2014-08-22
Start date
2014-08-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpitis. Diseases of pulp and periapical tissues

Interventions

Intervention 1: Forty intact premolar teeth will select from 10 healthy orthodontic patients that will candidates for extraction of four premolars
the teeth will randomiz for DPC (n=20) or PP (n=20). After anesthesia and isolation, a class I cavity was prepared and buccal pulp horn will expose using a high speed ½ round high speed bur under copi
Treatment - Drugs
Forty intact premolar teeth will select from 10 healthy orthodontic patients that will candidates for extraction of four premolars
for group 1: The buccal pulp horn exposure will pinpoint in size for DPC group
for group 2: whole head of the bur will enter into the pulpal horn in PP group
for goup 3:The half of the DPC group, will receive dexamethasone in "solution"
for group 4:The half PP group , will receive dexamethasone in "solution"

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The teeth must have no history of trauma; absence of caries; restorations; periodontal problems; Exclusion criteria: Patients with known allergy; sensitivity; contraindications for use of dexamethasone

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Calcified bridge. Timepoint: 2 months. Method of measurement: h and e staining.

Secondary

MeasureTime frame
Tissue reaction. Timepoint: 2 months. Method of measurement: microscope.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyed Amir Mousavi

Isfahan University of Medical Sciences

mousavi@dnt.mui.ac.ir+98 31 3673 6517

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026