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Evaluation of effectiveness of intravenous lidocaine in comparison to morphine sulfate in patients suffering from limb trauma

Evaluation of effectiveness of intravenous lidocaine in comparison to morphine sulfate in patients suffering from limb trauma who come to emergency department of Imam Khomeini Hospital between 01.01.2015 and 20.03.2015

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014080518698N1
Enrollment
50
Registered
2015-03-15
Start date
2014-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

limb pain secondary to trauma. Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)

Interventions

Intervention 1: Triple Blinded Randomized Clinical Trial. Intervention 2: First group will be treated by 0.1 mg/kg morphine sulfate( Daru Pakhsh CO. Tehran, Iran) via slow venous infusion . We calcu
Treatment - Drugs
Triple Blinded Randomized Clinical Trial
First group will be treated by 0.1 mg/kg morphine sulfate( Daru Pakhsh CO. Tehran, Iran) via slow venous infusion . We calculate NRS before treatment and 15. 30, 45 and 60 min after treatment.
second group will be treated by 1.5 mg/kg lidocaine( Caspian Daru CO, Rasht, Iran) via slow venous infusion . We calculate NRS before treatment and 15. 30, 45 and 60 min after treatment.

Sponsors

Tehran University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : age over 16 & less than 65 years old ; acute upper or lower limb trauma including soft tissue injury ,torsion,dislocation,fractures, as a main cause of arrival in ED ( less than 24 hrs from iniatiating of trauma event.) ; need to administer pain reilefer(NRS>5 /pain score over 5 ) exclusion criteria : altered mental status (glasgow coma scale <15) ; hemodynamic instability ( SBP=90, PR=60, RR=8 , 90% = O2 ) and in patient with hypertention ( 180 =SBP ) or (SBP=100) ; hypersensivity to lidocaein & morphine

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain level changing in patients. Timepoint: Every 15 min till one hour. Method of measurement: With Numeric Rating Scale that ask to the patient.

Secondary

MeasureTime frame
Time of pain relief in patients recieve lidocaine. Timepoint: Every 15 min till one hour. Method of measurement: With Numeric Rating Scale that ask to the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadid Hamrah

Tehran University Of Medical Sciences

hadid_ham@yahoo.com+98 912 326 5574

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026