Effects of Echinacea on Ventilator – Associated Pneumonia

Comparsion the effects of Echinacea and normalsaline mouthwashes on Ventilator Associated Pneumonia in intubated patients in intensive care units. Arak

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014080518694N1

Enrollment

Registered

2014-10-28

Start date

2014-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator Associated Pneumonia. Pneumonia in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Echinacea mouthwash 1%, 30cc,two times a day using a toothbrush for fifth days. Intervention 2: Control group: normal saline mouthwash using a toothbrush, 30cc,tw

Treatment - Drugs

Intervention group: Echinacea mouthwash 1%, 30cc,two times a day using a toothbrush for fifth days

Control group: normal saline mouthwash using a toothbrush, 30cc,two times a day using a toothbrush for fifth days

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: having a tracheal tube; aged 18-65 years; less than 12 hours of hospitalization in the intensive care unit before. Exclusion criteria: patients transferred from the intensive care unit; patients died before completion of the study; any damage caused by endotracheal intubation; airway or any other physical cause; antibiotic use before admission; admission in other units before intensive care unit; pregnancy; history of allergy to herbal substances; chronic diseases of immune system.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ventilator Associated Pneumonia. Timepoint: Before intervention and in the fifth day of intervention. Method of measurement: Clinical Pulmonary Infection Score (CPIS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Gholami Mehrabadi

Arak University of Medical Sciences

m.gholami@arakmu.ac.ir; m.mehrabadi.gholami@gmail.com.+98 86 3223 1169

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026