Multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Intervention 1: Intervention group: The duration of intervention in this clinical trial will be 12 weeks. People receiving nanocrocin supplements will receive 5.74 mg of crocin loaded on selenium nano
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: The desire of the person to participate in the study Definite dagnosis of relapsing-remitting MS based on the 2017 McDonald Diagnostic Criteria Age range 55-18 years EDSS less than 5.5 Education higher than diploma More than a month has passed since the last injection of corticosteroids (pulse therapy) More than a month has passed since the last recurrence of the disease
Exclusion criteria
Exclusion criteria: Having a neurological disease other than MS Pregnancy or breastfeeding Suffering from chronic gastrointestinal, liver, kidney, heart, respiratory and cancer diseases Being on a special diet Suffering from severe psychological disorders such as major depression History of allergies to saffron or its compounds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognition performance. Timepoint: At the beginning of study and the end of 12th week. Method of measurement: BICAMS test.;Plasma total antioxidant capacity. Timepoint: At the beginning of study and the end of 12th week. Method of measurement: Blood test.;Plasma malondialdehyde. Timepoint: At the beginning of study and the end of 12th week. Method of measurement: Blood test.;Glutathione reductase activity. Timepoint: At the beginning of study and the end of 12th week. Method of measurement: blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasim Rezaeimanesh
Shahid Beheshti University of Medical Sciences
Outcome results
None listed