Obtainability of intraoperative remifentanil infusion induced hyperalgesia and compare control methods pf post op pain with Morphine or Apotel.

Obtainability of intraoperative remifentanil infusion induced hyperagesia and compare control methods of post op pain with Morphine or Apotel.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014072618597N1

Enrollment

Registered

2015-03-12

Start date

2015-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing spinal surgery in which device will be used. Spondylosis and Other spondylopathies

Interventions

Intervention 1: Group I : Remifentanil ( maintenance) and Apotel ( end of surgery) According Methods. Intervention 2: Group II : Remifentanil ( maintenance) , Morphine ( end of surgery) Ac

Treatment - Drugs

Group I : Remifentanil ( maintenance) and Apotel ( end of surgery) According Methods

Group II : Remifentanil ( maintenance) , Morphine ( end of surgery) According Methods

Group III : Fentanyl ( maintenance) Apotel ( end of surgery) According Methods

Eligibility

Sex/Gender

All

Age

15 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients between the age of 15-75; with ASA class I or II. Exclusion criteria: patients with acute kidney failure; chronic kidney failure; hepatic dysfunction; patients addicted to drugs; alcohol and other medications.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: At Recovery Room, 6, 12, 24,48 hours after surgery. Method of measurement: Visual Analogue Scale.;Ramsey Sedation Scale. Timepoint: Recovery, 6, 12, 24,48 hours after surgery. Method of measurement: Ramsey Sedation Score Table.;Morphine consumption after surgery. Timepoint: Recovery, 6, 12, 24,48 hours after surgery. Method of measurement: Milligram.	—

Secondary

Measure	Time frame
Respiratory Depression. Timepoint: At Recovery Room, 6,12,24,48 hrs. after surgery. Method of measurement: Clinical Observation.;Post Operation Vomiting and Nausea (PONV). Timepoint: At Recovery Room, 6,12,24,48 hrs. after surgery. Method of measurement: Standard Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe sahraei

Sina Hospital

e.sahrai@ymail.com+98 919 550 5701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026