Ocular complications following the use of Vitamin A and simple eye ointment in non- ophthalmic surgery

Comparison of ocular complications following the use of Vitamin A and simple eye topical ointment in non-ophthalmic surgery during general anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014072418581N1

Enrollment

130

Registered

2015-12-11

Start date

2015-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye pain, Blurry vision, Tearing, Red eye, Photophobia, Foreign body sensation, Allergic reactions, Periorbital edema, Itchy, Sticking of the eyes together, Conjunctiva hyperemia, Scleral erythema, Corneal erosions. Postprocedural disorder of eye and adnexa, unspecified

Interventions

Intervention 1: Intervention group1: (Two standards common types of eye ointments simultaneously into one patient's eye during general anesthesia). Vitamin A ointment (Xerovit, containing 250 units pe

Prevention

Intervention group1: (Two standards common types of eye ointments simultaneously into one patient's eye during general anesthesia). Vitamin A ointment (Xerovit, containing 250 units per gram of vitam

Intervention group 2: (one type of common standard eye ointment into both patient's eye during general anesthesia). Vitamin A ointment is applied into both eyes of patients and simple eye ointment in

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: In this study, all patients undergoing general anesthesia for non-ophthalmic surgery are being studied. Exclusion criteria: Patients who have a history of ocular surgery; Patients who wear eye contact lenses; Patients who have visual acuity of less than 20/100; patients who have a history of ocular disease; Patients who are allergic to adhesive tape or eye ointment; Pregnant Women; Patients with conjunctivitis; ocular prosthesis; ocular hypoperfusion secondary to hypotension or anemia or using a beta blocker and a diuretic such as hydrochlorothiazide due to decrease in tear production base are excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Any type of eye complications as eye pain, Blurry vision, Tearing, Red eye, Photophobia, Foreign body sensation, Allergic reactions, Periorbital edema, Itchy, sticking of the eyes together, Conjunctiva hyperemia, Scleral erythema, Corneal erosions. Timepoint: 3to5 hours after general anesthesia, within the 24 hours after anesthesia, after discharge, more investigating in case of any complications. Method of measurement: Visual Analog Scale(VAS), Snellen Eye Chart, Schirmer's test,Scoring system for periorbital oedema, Oxford Schema.	—

Measure

Time frame

Any type of eye complications as eye pain, Blurry vision, Tearing, Red eye, Photophobia, Foreign body sensation, Allergic reactions, Periorbital edema, Itchy, sticking of the eyes together, Conjunctiva hyperemia, Scleral erythema, Corneal erosions. Timepoint: 3to5 hours after general anesthesia, within the 24 hours after anesthesia, after discharge, more investigating in case of any complications. Method of measurement: Visual Analog Scale(VAS), Snellen Eye Chart, Schirmer's test,Scoring system for periorbital oedema, Oxford Schema.

—

Secondary

Measure	Time frame
-. Timepoint: 3to5 hours after general anesthesia, within the 24 hours after anesthesia, after discharge, more investigating in case of any complications. Method of measurement: Visual Analog Scale(VAS), Snellen Eye Chart, Schirmer's test, Scoring system for periorbital oedema, Oxford Schema.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedehsara Bayesh

Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran

sarabayesh@yahoo.com; frgholami@gmail.com+98 912 124 2941

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026