poly cystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: patients in case group ,will receive Naltroxan 50 mg in capsule form per night. Intervention 2: in an other group Metformin 500 mg three thimes per day for at least six weeks before i
Treatment - Drugs
patients in case group ,will receive Naltroxan 50 mg in capsule form per night
in an other group Metformin 500 mg three thimes per day for at least six weeks before iui ,will be prescribed for patients.
No drug will be prescribed for control group unith definitive result of pregnancy
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
19 Years to 40 Years
Inclusion criteria
Inclusion criteria: stiExclusion criteria: 1-PCO diagnosed patients according to Roterdam criteria ? 2- Insulin Resistancy as HOMA index ? 3-BMI = 25-30 kg/m2? 4- age 1
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number & size of ovarian follicles after ovarian stimulation &out come of IUI. Timepoint: on th 11th day of menstrual cycle &14 day after IUI. Method of measurement: evaluation the number &size of follides on 11 th day of menstrual cycle & check of blood HCG for detection of pregnancy after 14 day from IUI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemical &clinical pregnancy &miscariage. Timepoint: 5-6 weeks after IUI. Method of measurement: Serum BHCG and transvaginal sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactdr Gooya Madadi
Shiraz University of Medical Sciences
Outcome results
None listed