Evaluation of different doses administration of clopidogrel in acute ischemic stroke

Comparison of clopidogrel loading dose with standard regime Acute Ischemic Stroke

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201407213106N18

Enrollment

Registered

2015-03-05

Start date

2014-08-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke. Brain stem stroke syndrome

Interventions

Intervention 1: Intervention group: recivied 300 mg clopidogrel at the first day. Intervention 2: Control group:recivied 75 mg clopidogrel and 225 mg placebo at the first day.

Treatment - Drugs

Placebo

Intervention group: recivied 300 mg clopidogrel at the first day.

Control group:recivied 75 mg clopidogrel and 225 mg placebo at the first day.

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criterion: the patient with acute ischemic stroke above 40 and under 80 years old. Exclusion criteria: hemorrhage; need to anticoagolant or heparin; platelet decrease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Aphasia and dysmotility. Timepoint: at the end 2 weeks. Method of measurement: NIHSS Score.	—

Secondary

Measure	Time frame
Unablility to move. Timepoint: At the of 2nd week. Method of measurement: Barthel index and Modified rankin scale.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026