The effects of pentoxifylline in control of hypertension

Evaluation of pentoxifylline on blood tension rate in patients with hypertension; randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201407208307N8

Enrollment

100

Registered

2016-12-20

Start date

2016-03-11

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hypertension. Condition 2: Hypertension. Essential (primary) hypertension Hypertensive heart disease without (congestive) heart failure

Interventions

Intervention 1: Intervention: 1200 mg oral pentoxifylline in three divided doses plus the standard treatment. Intervention 2: Control group: All patients will be received their standard treatment.

Treatment - Drugs

Intervention: 1200 mg oral pentoxifylline in three divided doses plus the standard treatment.

Control group: All patients will be received their standard treatment.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: outpatients with primary hypertension; patients with 18 years old and over; consented patients. Exclusion criteria: secondary hypertension; pregnancy; liver failure; kidney failure; heart failure; pentoxifylline or anti-hypertensive drugs contraindications.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: befor, 1 and 3 months after intervention. Method of measurement: Mercury Manometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Taher Entezari-maleki

Tabriz University of Medical Sciences

tentezari@gmail.com+98 41 3334 4798

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026