Condition 1: Proximal gastric cancer. Condition 2: Gastro-oesophageal cancer. Fundus of stomach Gastro-oesophagea cancerl
Conditions
Interventions
All patients with locally advanced proximal gastric cancer and junction esophagogastric cancer receive Preoperative Chemoradiation therapy before surgery are candidates with a positive biopsy . Before
Treatment - Other
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The main inclusion criteria: All patients with locally advanced proximal gastric cancer and esophagogastric cancer who have positive biopsy results and has been filled the consent form informally. The main exclusion criteria: patients (illness) at stage I and IV; patient dissatisfaction; comorbid diseases that prevent oncologic treatment; previous cancer; previous chemotherapy or radiotherapy; hepatic and renal dysfunction that prevents oncologic treatments; Performance status 3,4 ECOG
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of resectability rate and tumor response in patients with locally advanced proximal gastric cancer and esophagogastric cancer treated with neoadjuvant chemoradiotheraphy. Timepoint: Pathologic Evaluation of surgical specimen. Method of measurement: Pathologic response. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of surgical copmplication. Timepoint: Post operation. Method of measurement: Incisional leek,post op mortality. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Emadi Torghabeh
Omid Hospital
Outcome results
None listed