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Azithromycin's effect on periodontitis

Effect of systemic administration of azithromycin following non-surgical treatment in patients with moderate chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014071518493N1
Enrollment
40
Registered
2015-03-06
Start date
2015-02-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic pericoronitis Periodontitis: NOS complex simplex

Interventions

Intervention 1: Intervention group:Administrating azithromycin 250 mg for 3 days,2 pills per day,Scaling Root Planing ,Oral hygiene instruction. Intervention 2: Control group:Administrating placebo fo
Treatment - Drugs
Placebo
Intervention group:Administrating azithromycin 250 mg for 3 days,2 pills per day,Scaling Root Planing ,Oral hygiene instruction.
Control group:Administrating placebo for 3 days,2 pills per day.Scaling Root Planing,oral hygiene instructions.

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:non smoker patient;18 years old or more;with at least 20 teeth Exclusion criteria:pregnancy;antibiotic therapy in the last 3 months;use of any antibiotics during the study;allergy to macrolids;use of warfarin or cyclosporins;immune system insufficiency

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pocket depth. Timepoint: pre treatment,2 weeks after treatment,1 month after treatment,3 month after treatment. Method of measurement: distance between gingiva margin to base of pocket by williams probe.;Clinical attachment level. Timepoint: pre treatment,2 weeks after treatment,1 month after treatment,3 month after treatment. Method of measurement: distance between cej to base of pocket by williams probe.;Gingival index. Timepoint: pre treatment,2 weeks after treatment,1 month after treatment,3 month after treatment. Method of measurement: by O'Leary technique.;Plaque index. Timepoint: pre treatment,2 weeks after treatment,1 month after treatment,3 month after treatment. Method of measurement: by O'Leary technique.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoroosh Mokhtari

Zahedan University of Medical Sciences

soroosh.mokhtari@yahoo.com+98 54 3341 4004

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026