Comparison of vascular complications in carotid artery stenting with and without the use of embolic protection device

Evaluation of vascular complication incidence in patients with Internal Carotid Artery(ICA) stenosis treated with Carotid Artery Stenting (CAS) without Embolic protection device (EPD) in comparison to CAS with EPD

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140712018457N7

Enrollment

Registered

2022-11-14

Start date

2022-10-07

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Stenosis. Occlusion and stenosis of carotid artery

Interventions

Intervention 1: Intervention group: Carotid artery stenting with an protective device in patient with carotid artery stenosis (A device used to reduce the risk of embolic complications during carotid

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients over 18 years old Internal carotid artery stenosis more than 70% in asymptomatic patients Internal carotid artery stenosis more than 50% in symptomatic patients

Exclusion criteria

Exclusion criteria: Proper candidate for Endarterectomy Renal failure History of allergy to radio contrast agents.

Design outcomes

Primary

Measure	Time frame
Brain stroke. Timepoint: Twenty-four hours after treatment (early complication), 6 months and 2 years after treatment. Method of measurement: Physical examination and history taking, Magnetic Resonance Imaging (MRI).;Myocardial Infarction. Timepoint: Twenty-four hours after treatment (early complication), 6 months and 2 years after treatment. Method of measurement: Physical examination and history taking, Electrocardiography.;New lesions in MR imaging (Diffusion-weighted imaging). Timepoint: Twenty-four hours after treatment. Method of measurement: MR Imaging.;Carotid artery restenosis. Timepoint: 6 months and 2years after treatment. Method of measurement: Carotid artery ultrasonography.;Mortality. Timepoint: Follow-up of patients 24 hours after treatment, 6 months and 2 years after treatment. Method of measurement: Physical examination and history taking, telephone follow-up.	—

Measure

Time frame

Brain stroke. Timepoint: Twenty-four hours after treatment (early complication), 6 months and 2 years after treatment. Method of measurement: Physical examination and history taking, Magnetic Resonance Imaging (MRI).;Myocardial Infarction. Timepoint: Twenty-four hours after treatment (early complication), 6 months and 2 years after treatment. Method of measurement: Physical examination and history taking, Electrocardiography.;New lesions in MR imaging (Diffusion-weighted imaging). Timepoint: Twenty-four hours after treatment. Method of measurement: MR Imaging.;Carotid artery restenosis. Timepoint: 6 months and 2years after treatment. Method of measurement: Carotid artery ultrasonography.;Mortality. Timepoint: Follow-up of patients 24 hours after treatment, 6 months and 2 years after treatment. Method of measurement: Physical examination and history taking, telephone follow-up.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Alborzi

Tehran University of Medical Sciences

mahsaalborzi94@gmail.com+98 21 6658 1579

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026