Effect of three different doses of oxytocin infusion on hemodynamic changes in cesarean delivery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201407082963N18

Enrollment

120

Registered

2014-08-11

Start date

2012-03-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemodynamic changes in cesarean delivery. Delivery by elective caesarean section

Interventions

Intervention 1: case group 1: oxytocin 10 units. Intervention 2: case group 2: oxytocin 40 units. Intervention 3: case group 3: oxytocin 80 units.

Treatment - Drugs

case group 1: oxytocin 10 units

case group 2: oxytocin 40 units

case group 3: oxytocin 80 units

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: included criteria: all Patients age 18-35 years old and BMI 20-35 by American Society of Anesthesia (ASA) physical status I underwent for non emergency repeated cesarean delivery under spinal anesthesia. excluded criteria: BMI>35; chronic hypertension; placenta previa; placenta precrata; placenta abruption; placental collaps; gestational age <28 weeks; polyhydroamnious; thrombocytopenia (plt<70000); risk factors of bleeding and history of tocolytic drugs and Aspirin use.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Diastolic blood pressure. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.;Systolic blood pressure. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.;Heart rate. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.;Mean arterial blood pressure. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.	—

Measure

Time frame

Diastolic blood pressure. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.;Systolic blood pressure. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.;Heart rate. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.;Mean arterial blood pressure. Timepoint: 30 seconds before oxytocin infusion and each 5 minutes to 30 minutes after the that. Method of measurement: by sphygmomanometer.

—

Secondary

Measure	Time frame
Uterine tone. Timepoint: 5 to 15 minutes after placenta removal. Method of measurement: by physical exam.;Nausia and vomiting. Timepoint: after awarness of patient. Method of measurement: by direct asking.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shekofeh Behdad

Shahid Sadoughi University of Medical Sciences

behdad90@gmail.com+98 35 1822 4000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026